Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095445 | 0.82 | KCNK3 (0.62) | MAPTGAANPC1POLBRAB9A | |
| SCHEMBL28960892 | 0.81 | HDAC8 (0.46) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL17667736 | 0.78 | MAPT (0.44) | MAPTGAASMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL13921663 | 0.78 | APP (0.36) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL28569398 | 0.77 | GAA (0.34) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL28580318 | 0.77 | ALDH1A1 (0.40) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL13884642 | 0.76 | FOLH1 (0.54) | ALDH1A1NPSR1 | |
| SCHEMBL13887515 | 0.76 | GRIN2D (0.43) | GAASMN1; SMN2HDAC1HDAC2HDAC3 | |
| SCHEMBL30565264 | 0.75 | ALDH1A1 (0.52) | MAPTALDH1A1MAPK1NPSR1NPC1 | |
| SCHEMBL1028484 | 0.75 | PDK1 (0.56) | MAPTGAASMN1; SMN2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636817-A | Isatin derivative containing triazole ring and preparation method and application thereof | 山东大学 | 2023-01-24 | — | — | CN | claimed |
| CN-115636817-A | Isatin derivative containing triazole ring and preparation method and application thereof | 山东大学 | 2023-01-24 | — | — | CN | disclosed |