Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571084 | 0.80 | HDAC8 (0.40) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL13921663 | 0.79 | APP (0.36) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL28580318 | 0.78 | ALDH1A1 (0.40) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL13887515 | 0.77 | GRIN2D (0.43) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL28945868 | 0.77 | MAPT (0.42) | GAAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL28379715 | 0.73 | ALDH1A1 (0.38) | GAA | |
| SCHEMBL29111184 | 0.72 | EGFR (0.36) | — | |
| SCHEMBL31527650 | 0.71 | IKBKB (0.46) | — | |
| SCHEMBL13855831 | 0.71 | HTR3E (0.52) | — | |
| SCHEMBL13921656 | 0.70 | GRK2 (0.35) | HDAC1HDAC2HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636817-A | Isatin derivative containing triazole ring and preparation method and application thereof | 山东大学 | 2023-01-24 | — | — | CN | claimed |
| CN-115636817-A | Isatin derivative containing triazole ring and preparation method and application thereof | 山东大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-109705095-B | Fused ring p-benzoquinone CDC25 protein phosphatase inhibitor containing triazole ring, and preparation method and application thereof | 山东大学 | 2021-06-08 | — | — | CN | disclosed |