SCHEMBL28945993

SCHEMBL28945993

c1ccc(-c2ccc(C3c4ccccc4-c4ccccc43)c3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.41
CSF1R P07333 1/20 0.41
FGFR1 P11362 1/20 0.41
PDGFRA P16234 1/20 0.41
LTK P29376 1/20 0.41
KDR P35968 1/20 0.41
MAPK8 P45983 1/20 0.41
CSNK1A1 P48729 1/20 0.41
LIMK1 P53667 1/20 0.41
CDK5 Q00535 1/20 0.41
ACVR1 Q04771 1/20 0.41
TNK2 Q07912 1/20 0.41
AURKB Q96GD4 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
PLG P00747 1/20 0.39
METAP2 P50579 1/20 0.38
TNF P01375 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22272286 0.85 MAPK1 (0.38) CSF1RFGFR1KDRAURKBALDH1A1
SCHEMBL22272290 0.84 HSD17B1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1CA12
SCHEMBL2594422 0.83 ALDH1A1 (0.50) ALDH1A1HSD17B10CHRNB2CHRNA4HTR2A
SCHEMBL28460847 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10CHRNB2CHRNA4HTR2A
SCHEMBL22272279 0.80 ALDH1A1 (0.47) ALDH1A1HSD17B10TNFHPGDMAPK1
SCHEMBL2391683 0.78 ALDH1A1 (0.52) MAP4K4CSF1RFGFR1PDGFRALTK
SCHEMBL6675754 0.77 KDM1A (0.53) ALDH1A1HSD17B10HTR2AHPGDCYP2A6
SCHEMBL22272274 0.77 ALDH1A1 (0.39) MAP4K4CSF1RFGFR1PDGFRALTK
SCHEMBL22272302 0.76 CYP1A2 (0.40) HTR2AMAPK1
SCHEMBL3415539 0.75 ALDH1A1 (0.53) MAP4K4CSF1RFGFR1PDGFRALTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115636889-B Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2024-03-01 CN claimed
CN-115636994-B Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2024-03-01 CN claimed
CN-115636994-A Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2023-01-24 CN claimed
CN-115636889-A Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2023-01-24 CN claimed
CN-115636889-B Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2024-03-01 CN disclosed
CN-115636994-B Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2024-03-01 CN disclosed
CN-115636994-A Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2023-01-24 CN disclosed
CN-115636889-A Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2023-01-24 CN disclosed