Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460847 | 0.92 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HTR2ADPP4MAPK1 | |
| SCHEMBL28757847 | 0.89 | BRD4 (0.44) | ALDH1A1HSD17B10HTR2ADPP4BRD4 | |
| SCHEMBL28945993 | 0.83 | MAP4K4 (0.41) | ALDH1A1HSD17B10HTR2ADPP4MAPK1 | |
| SCHEMBL27372447 | 0.78 | KDM1A (0.47) | ALDH1A1HSD17B10HTR2AMAPK1HPGD | |
| SCHEMBL16544752 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HTR2ADPP4MAPK1 | |
| SCHEMBL28773429 | 0.77 | KDM1A (0.50) | HTR2AGPR3 | |
| Biphenyl SCHEMBL21382703 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HTR2ADPP4MAPK1 | |
| SCHEMBL150218 | 0.77 | CHRNB2 (0.44) | ALDH1A1HSD17B10HTR2ADPP4MAPK1 | |
| SCHEMBL25171318 | 0.76 | LMNA (0.54) | ALDH1A1HSD17B10HTR2AMAPK1GPR3 | |
| SCHEMBL70993 | 0.76 | LMNA (0.54) | ALDH1A1HSD17B10HTR2AMAPK1GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383861-A2 | ARYLATION METHOD | Umicore AG & Co. KG (DE) | 2018-10-10 | — | — | EP | claimed |
| EP-3383861-A2 | ARYLATION METHOD | Umicore AG & Co. KG (DE) | 2018-10-10 | — | — | EP | disclosed |
| US-20180212149-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| EP-1690847-B1 | pi-conjugated compound having cardo structure, process for the preparation thereof and use thereof | TOSOH CORP (JP) | 2016-06-22 | — | — | EP | disclosed |
| US-9269911-B2 | Organic light-emitting device | CANON KABUSHIKI KAISHA (JP) | 2016-02-23 | — | — | US | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| EP-2564441-A1 | ORGANIC LIGHT-EMITTING DEVICE | Canon Kabushiki Kaisha (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20130037791-A1 | ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2013-02-14 | — | — | US | disclosed |
| WO-2011136156-A1 | ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | ALDH1A1 33/4885HSD17B10 1957/4885HTR2A 4494/4885 |
| US-20180212149-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | ALDH1A1 33/4885HSD17B10 1957/4885HTR2A 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.