Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307336 | 0.93 | KDM4E (0.42) | LMNAMAPTALDH1A1POLBMEN1 | |
| SCHEMBL28946158 | 0.88 | L3MBTL1 (0.38) | LMNAMAPTALDH1A1PTGER4RAB9A | |
| SCHEMBL28964122 | 0.85 | L3MBTL1 (0.44) | LMNAMAPTALDH1A1HCAR3RAB9A | |
| SCHEMBL28946165 | 0.83 | L3MBTL1 (0.54) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL28946177 | 0.82 | PGK1 (0.46) | LMNAMAPTALDH1A1HCAR3POLB | |
| SCHEMBL28946162 | 0.81 | MAPT (0.48) | LMNAMAPTALDH1A1RAB9ATXNRD1 | |
| SCHEMBL8246245 | 0.80 | MAPT (0.59) | LMNAMAPTALDH1A1HCAR3PTGER4 | |
| SCHEMBL28946146 | 0.80 | NPC1 (0.58) | LMNAMAPTRAB9ATXNRD1KMT2A | |
| SCHEMBL28946150 | 0.79 | PKM (0.46) | LMNAMAPTALDH1A1RAB9APOLB | |
| SCHEMBL28946147 | 0.78 | MAPT (0.46) | LMNAMAPTRAB9APOLBTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | disclosed |