Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946150 | 0.89 | PKM (0.46) | MAPTPKMNPC1RAB9APOLB | |
| SCHEMBL28946146 | 0.88 | NPC1 (0.58) | MAPTPKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28946162 | 0.86 | MAPT (0.48) | MAPTPKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28946169 | 0.82 | PRKCQ (0.45) | MAPTPKMNPC1RAB9ATXNRD1 | |
| SCHEMBL28964122 | 0.81 | L3MBTL1 (0.44) | MAPTPKMNPC1RAB9APOLB | |
| SCHEMBL28946165 | 0.79 | L3MBTL1 (0.54) | MAPTPKMPOLBSMN1; SMN2TXNRD1 | |
| SCHEMBL28946177 | 0.79 | PGK1 (0.46) | MAPTPKMPOLBSMN1; SMN2TXNRD1 | |
| SCHEMBL28946161 | 0.78 | LMNA (0.48) | MAPTPKMRAB9APOLBTXNRD1 | |
| SCHEMBL28946158 | 0.76 | L3MBTL1 (0.38) | MAPTPKMNPC1RAB9APOLB | |
| SCHEMBL28307336 | 0.76 | KDM4E (0.42) | MAPTPOLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | disclosed |