Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855702 | 0.74 | MAPT (0.42) | ALDH1A1SMN1; SMN2L3MBTL1LMNAGAA | |
| SCHEMBL2868181 | 0.73 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNAGAAMMP8 | |
| SCHEMBL27856197 | 0.73 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2L3MBTL1LMNAGAA | |
| SCHEMBL5541260 | 0.71 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL15534741 | 0.71 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL15534740 | 0.71 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8149342 | 0.69 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAGAAMMP8 | |
| SCHEMBL2858639 | 0.69 | CPB2 (0.43) | ALDH1A1L3MBTL1LMNACYP1A2GAA | |
| SCHEMBL6755582 | 0.69 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNACYP1A2GAA | |
| SCHEMBL27631184 | 0.69 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAGAAMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |