Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4890866 | 0.87 | HTR2C (0.47) | MAOAMAOBKDM1ASLC6A3OPRM1 | |
| SCHEMBL17729483 | 0.85 | MAOA (0.50) | MAOAMAOBKDM1ASLC6A3OPRM1 | |
| SCHEMBL28947779 | 0.79 | SLC6A3 (0.43) | MAOAMAOBSLC6A3OPRM1TACR1 | |
| Hydrochloric Acid SCHEMBL31412616 | 0.78 | SLC6A3 (0.42) | MAOAMAOBSLC6A3TACR1DAO | |
| SCHEMBL1814719 | 0.77 | DRD2 (0.47) | MAOAMAOBKDM1ASLC6A3OPRM1 | |
| SCHEMBL15819350 | 0.77 | HTR2A (0.59) | MAOAMAOBSLC6A3OPRM1TACR1 | |
| SCHEMBL28122494 | 0.73 | HTR2C (0.44) | MAOAMAOBKDM1ASLC6A3OPRM1 | |
| SCHEMBL27100094 | 0.73 | OPRM1 (0.45) | MAOAMAOBKDM1ASLC6A3OPRM1 | |
| SCHEMBL653874 | 0.73 | DRD2 (0.59) | MAOAMAOBKDM1ASLC6A3OPRM1 | |
| Hydrochloric Acid SCHEMBL17224460 | 0.72 | HTR2A (0.45) | MAOAMAOBKDM1ASLC6A3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698009-A | CD73 inhibiting 2,4-dioxopyrimidine compounds | 吉利德科学公司 | 2023-02-03 | — | — | CN | disclosed |