Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 4/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23994439 | 0.76 | TP53 (0.48) | MAPTELANESLC6A2CRHR1SLC6A4 | |
| SCHEMBL836635 | 0.73 | PGR (0.36) | MAPTSLC6A2PDE7ATP53PGR | |
| SCHEMBL30224652 | 0.71 | BACE1 (0.38) | MAPTELANETP53PGRBACE1 | |
| SCHEMBL23992898 | 0.71 | BACE1 (0.38) | MAPTELANETP53PGRBACE1 | |
| SCHEMBL28321469 | 0.68 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL31241690 | 0.66 | BCHE (0.39) | MEN1KMT2A | |
| SCHEMBL30418651 | 0.66 | BCHE (0.39) | MEN1KMT2A | |
| SCHEMBL23994742 | 0.66 | KMT2A (0.35) | SLC6A2PDE7ACTSDBACE1KMT2A | |
| SCHEMBL13341336 | 0.65 | BACE1 (0.32) | CTSDBACE1 | |
| SCHEMBL23992901 | 0.64 | RXRA (0.34) | MAPTTP53PGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698009-A | CD73 inhibiting 2,4-dioxopyrimidine compounds | 吉利德科学公司 | 2023-02-03 | — | — | CN | disclosed |