Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780256 | 0.88 | AKR1B1 (0.41) | AKR1B1BACE1GABRA1GABRB2MEN1 | |
| SCHEMBL10448034 | 0.83 | GABRA1 (0.50) | AKR1B1GABRA1GABRB2MEN1MAPT | |
| SCHEMBL4987129 | 0.81 | ALDH1A1 (0.50) | AKR1B1BACE1GABRA1GABRB2MEN1 | |
| SCHEMBL10587415 | 0.79 | BACE1 (0.50) | AKR1B1BACE1GABRA1GABRB2MEN1 | |
| SCHEMBL28972909 | 0.78 | BACE1 (0.48) | AKR1B1BACE1GABRA1GABRB2MEN1 | |
| SCHEMBL13030493 | 0.77 | SRD5A1 (0.44) | AKR1B1GABRA1GABRB2MEN1MAPT | |
| SCHEMBL6013229 | 0.77 | GABRA1 (0.52) | AKR1B1GABRA1GABRB2MEN1MAPT | |
| SCHEMBL1413853 | 0.77 | SRD5A1 (0.49) | AKR1B1GABRA1GABRB2MEN1MAPT | |
| SCHEMBL30499023 | 0.77 | GABRA1 (0.46) | AKR1B1BACE1GABRA1GABRB2MEN1 | |
| SCHEMBL27533456 | 0.77 | GABRA1 (0.46) | AKR1B1BACE1GABRA1GABRB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698139-A | Crosslinkable organosiloxane-modified reaction resins | 瓦克化学股份公司 | 2023-02-03 | — | — | CN | disclosed |