Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28948634 | 0.78 | HCAR3 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL28948635 | 0.76 | VCAM1 (0.46) | VCAM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2650207 | 0.68 | VCAM1 (0.55) | VCAM1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL27521624 | 0.68 | VCAM1 (0.44) | VCAM1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL28495668 | 0.68 | VCAM1 (0.60) | VCAM1ALDH1A1MAPTMAPK1THRB | |
| SCHEMBL7973695 | 0.68 | MAPT (0.61) | VCAM1ALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL11875032 | 0.67 | VCAM1 (0.53) | VCAM1ALDH1A1SMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL30729425 | 0.66 | MAPT (0.59) | VCAM1ALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL11875635 | 0.66 | ALDH1A1 (0.44) | VCAM1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL28683817 | 0.66 | VCAM1 (0.54) | VCAM1ALDH1A1MAPTLMNARAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105601-B | Benzenesulfonamide derivatives and related FERROSTATIN-1 analogs as cell death inhibitors | 维伯VZW公司 | 2022-11-18 | — | — | CN | disclosed |