Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.43 |
| ▸ | VCP | P55072 | 2/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane Carboxamide SCHEMBL28819581 | 0.94 | OPRM1 (0.44) | NR1H4VCPOPRM1OPRL1OPRD1 | |
| SCHEMBL29880909 | 0.89 | PTGS2 (0.46) | NR1H4PTGS2CTSKCTSS | |
| Cyclohexane Carboxamide SCHEMBL28819715 | 0.86 | NR1H4 (0.49) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819590 | 0.86 | NR1H4 (0.49) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819682 | 0.85 | NR1H4 (0.49) | NR1H4OPRM1OPRD1OPRK1OGFRL1 | |
| Cyclohexane Carboxamide SCHEMBL28819611 | 0.85 | NR1H4 (0.59) | NR1H4 | |
| SCHEMBL3568943 | 0.85 | NR1H4 (0.62) | NR1H4C5AR1OPRM1OPRL1 | |
| Cyclohexane Carboxamide SCHEMBL28948660 | 0.84 | NR1H4 (0.48) | NR1H4VCPOPRM1OPRD1OPRK1 | |
| Cyclohexane Carboxamide SCHEMBL28819483 | 0.84 | NR1H4 (0.48) | NR1H4VCPOPRM1OPRD1OPRK1 | |
| Cyclohexane Carboxamide SCHEMBL28819722 | 0.84 | NR1H4 (0.44) | NR1H4VCPOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |