Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29881247 | 0.92 | OPRM1 (0.44) | PTGS2CTSKCTSSNR1H4PTGER4 | |
| Cyclohexane Carboxamide SCHEMBL28948656 | 0.89 | NR1H4 (0.43) | PTGS2CTSKCTSSNR1H4 | |
| SCHEMBL3568943 | 0.84 | NR1H4 (0.62) | NR1H4 | |
| SCHEMBL29880929 | 0.82 | ALDH1A1 (0.46) | NR1H4PTGER4HDAC1HDAC8HDAC6 | |
| SCHEMBL29880945 | 0.81 | KDM4E (0.50) | NPC1NR1H4PTGER4HDAC1HDAC8 | |
| SCHEMBL29880832 | 0.81 | NR1H4 (0.56) | NPC1NR1H4KDM4EALDH1A1LMNA | |
| SCHEMBL29881017 | 0.81 | NR1H4 (0.56) | NPC1NR1H4KDM4EALDH1A1LMNA | |
| SCHEMBL29881223 | 0.80 | PTGER4 (0.45) | NR1H4PTGER4HDAC1HDAC8HDAC6 | |
| SCHEMBL29881716 | 0.80 | KDM4E (0.44) | NR1H4PTGER4HDAC1HDAC8HDAC6 | |
| SCHEMBL29880939 | 0.80 | MAPK10 (0.48) | NR1H4PTGER4HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |