Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29524794 | 1.00 | ENPP2 (0.33) | ENPP2ADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL29951757 | 0.80 | ENPP2 (0.41) | ENPP2FAAHCA1CA2LMNA | |
| SCHEMBL4013443 | 0.80 | ENPP2 (0.41) | ENPP2FAAHCA1CA2LMNA | |
| SCHEMBL25745449 | 0.79 | ENPP2 (0.42) | ENPP2 | |
| SCHEMBL29955624 | 0.78 | MAPT (0.33) | ENPP2FAAHCA1CA2LMNA | |
| SCHEMBL29956604 | 0.76 | CYP1A2 (0.32) | ENPP2FAAHCA1CA2LMNA | |
| SCHEMBL4384 | 0.73 | CES2 (0.43) | ENPP2HPGDCES2CES1 | |
| SCHEMBL29399046 | 0.73 | CES2 (0.43) | ENPP2HPGDCES2CES1 | |
| SCHEMBL28971466 | 0.72 | GABRA1 (0.38) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL22905245 | 0.71 | GABRA1 (0.46) | FAAHCA1CA2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |