SCHEMBL4384

SCHEMBL4384

OB(O)c1cccc(F)c1F

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
BCHE P06276 1/20 0.43
ENPP2 Q13822 1/20 0.38
HPGD P15428 1/20 0.37
ERN1 O75460 1/20 0.35
ACHE P22303 1/20 0.35
NFE2L2 Q16236 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29399046 1.00 CES2 (0.43) CES2CES1BCHEENPP2HPGD
Hydrochloric Acid SCHEMBL29017070 0.98 CES2 (0.41) CES2CES1BCHEENPP2HPGD
SCHEMBL25745449 0.87 ENPP2 (0.42) ENPP2ACHE
SCHEMBL1074082 0.85 CES2 (0.43) CES2CES1BCHEHPGDERN1
SCHEMBL7203384 0.82 LIPG (0.41) CES2CES1BCHE
SCHEMBL8611022 0.79 CES2 (0.39) CES2CES1BCHEENPP2HPGD
SCHEMBL1359168 0.79 CES2 (0.41) CES2CES1BCHEHPGDERN1
SCHEMBL30464898 0.79 CES2 (0.41) CES2CES1BCHEHPGDERN1
SCHEMBL31282464 0.79 CES2 (0.41) CES2CES1BCHEHPGDERN1
SCHEMBL29468967 0.79 ENPP2 (0.46) CES2CES1ENPP2ACHENFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1839 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-117924295-A Furimazine derivative and preparation method and application thereof 广州博鹭腾生物科技有限公司 2024-04-26 CN claimed
WO-2024016826-A1 6-POSITION SUBSTITUTED DIHYDROBENZO[E][1,2,3]OXATHIAZINE 2,2-DIOXIDE COMPOUND, PREPARATION THEREFOR, AND USE THEREOF 杭州市第七人民医院 2024-01-25 WO claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
CN-114230552-B Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate 江苏广域化学有限公司 2023-11-03 CN claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-1923385-B1 Iridium complex, carbazole derivatives and copolymer having the same KWANGJU INST SCI & TECH (KR) 2009-05-27 EP claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
US-20080177084-A1 IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-24 US claimed
EP-1923385-A1 Iridium complex, carbazole derivatives and copolymer having the same Gwangju Institute of Science and Technology (KR) 2008-05-21 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
WO-2006101779-A2 NON-AQUEOUS ELECTROLYTES FOR LITHIUM ION BATTERIES THE UNIVERSITY OF CHICAGO (US) 2006-09-28 WO claimed
US-7037905-B2 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2006-05-02 US claimed
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2004-03-18 US claimed
WO-2003105860-A1 PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 2003-12-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof LIPE, CEL, LIPA CES2 18/4885CES1 9/4885BCHE 15/4885
US-20080177084-A1 IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME INTS9, HIRIP3, HELZ CES2 3949/4885CES1 4170/4885BCHE 4204/4885
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy GFER, MUC1, CTH CES2 1317/4885CES1 1971/4885BCHE 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.