Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28050047 | 0.86 | DAO (0.43) | PTGS2LMNANPC1MAPTMMP9 | |
| SCHEMBL28049926 | 0.82 | PTGS2 (0.43) | PTGS2LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL16228972 | 0.78 | PTGS2 (0.50) | PTGS2LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL16228971 | 0.78 | PTGS2 (0.50) | PTGS2LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28949611 | 0.78 | KDM4E (0.57) | PTGS2LMNANPC1RAB9AMAPT | |
| SCHEMBL14718728 | 0.72 | DAO (0.51) | LMNANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL9605425 | 0.71 | PTGS1 (0.59) | PTGS2LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28049929 | 0.70 | MMP9 (0.43) | PTGS2LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL9605424 | 0.67 | LCK (0.55) | PTGS2APPRELADRD1MAPK1 | |
| SCHEMBL11443825 | 0.65 | F3 (0.59) | PTGS2LMNANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103748079-B | Pyridazinone mixture and the purposes as DAAO inhibitor thereof | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-03-16 | — | — | CN | disclosed |