Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735543 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTTP53HPGDHTT | |
| SCHEMBL28950551 | 0.83 | POLB (0.51) | ALDH1A1MAPTGAALMNAGRM2 | |
| SCHEMBL28950554 | 0.83 | POLB (0.51) | ALDH1A1MAPTGAALMNAGRM2 | |
| SCHEMBL10920872 | 0.77 | LMNA (0.45) | ALDH1A1MAPTTP53HPGDHTT | |
| SCHEMBL10742539 | 0.75 | RAB9A (0.42) | ALDH1A1MAPTTP53HPGDGAA | |
| SCHEMBL10742552 | 0.75 | RAB9A (0.42) | ALDH1A1MAPTTP53HPGDGAA | |
| SCHEMBL30777491 | 0.74 | TP53 (0.47) | TP53HTTGAAGRM2TSHR | |
| SCHEMBL28831007 | 0.71 | RXFP1 (0.41) | MAPTLMNATSHRMEN1KMT2A | |
| SCHEMBL28831010 | 0.71 | RXFP1 (0.41) | MAPTLMNATSHRMEN1KMT2A | |
| SCHEMBL29187457 | 0.71 | ALOX15 (0.45) | ALDH1A1MAPTTP53HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4704385-A | MONOCYCLIC BETA-LACTAM ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1987-11-03 | — | — | US | disclosed |
| US-4678782-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1987-07-07 | — | — | US | disclosed |
| US-4647558-A | MONOCYCLIC B-LACTAM ANTIBIOTIC | BEECHAM GROUP P.L.C. (GB) | 1987-03-03 | — | — | US | disclosed |
| EP-0088488-B1 | ANTIBACTERIAL AGENTS, THEIR PREPARATION AND USE | BEECHAM GROUP PLC (GB) | 1986-10-01 | — | — | EP | disclosed |
| EP-0088488-A1 | Antibacterial agents, their preparation and use | BEECHAM GROUP PLC (GB) | 1983-09-14 | — | — | EP | disclosed |
| EP-0086563-A1 | Antibacterial agents, their preparation and use | BEECHAM GROUP PLC (GB) | 1983-08-24 | — | — | EP | disclosed |