Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14254923 | 0.82 | LTB4R (0.37) | MAPTL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL16419678 | 0.82 | ALDH1A1 (0.48) | L3MBTL1SYKMAPK1TDP1ALDH1A1 | |
| SCHEMBL15699370 | 0.81 | CTSK (0.48) | MAPTSYK | |
| SCHEMBL952619 | 0.81 | CTSK (0.48) | MAPTSYK | |
| SCHEMBL952620 | 0.81 | CTSK (0.48) | MAPTSYK | |
| SCHEMBL14596703 | 0.81 | AAK1 (0.36) | MAPTL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL13561435 | 0.80 | LTA4H (0.41) | L3MBTL1MAPK1TDP1LTA4HALDH1A1 | |
| SCHEMBL28950694 | 0.80 | AMPD3 (0.40) | MAPTL3MBTL1POLBSYKMAPK1 | |
| SCHEMBL30019063 | 0.80 | ALDH1A1 (0.42) | MAPTL3MBTL1POLBSYKMAPK1 | |
| SCHEMBL30019078 | 0.80 | ALDH1A1 (0.42) | MAPTL3MBTL1POLBSYKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4143189-A1 | MACROCYCLIC INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115551862-A | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2022-12-30 | — | — | CN | disclosed |