Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204919 | 0.67 | GPR35 (0.43) | GPR35KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16749643 | 0.66 | GPR35 (0.62) | GPR35KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28695182 | 0.65 | GPR35 (0.46) | GPR35KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12606667 | 0.64 | GPR35 (1.00) | GPR35KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1623178 | 0.63 | GPR35 (0.44) | GPR35KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14739013 | 0.62 | ELANE (0.36) | KDM4EALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL9952327 | 0.62 | ELANE (0.45) | KDM4EGLARORC | |
| SCHEMBL3636090 | 0.61 | ELANE (0.45) | ALDH1A1MEN1KMT2ALMNAAURKA | |
| SCHEMBL3518728 | 0.61 | CHEK1 (0.39) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9953073 | 0.61 | ELANE (0.40) | KDM4EALDH1A1MEN1KMT2ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682553-B1 | THIENOPYRAZOLES | AVENTIS PHARMA INC (US) | 2010-05-19 | — | — | EP | disclosed |