SCHEMBL16749643

SCHEMBL16749643

O=C(O)c1cc2c(s1)c1cc(C(=O)O)sc1c1cc(C(=O)O)sc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 4/20 0.62
DAO P14920 8/20 0.48
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 5/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 2/20 0.48
BCL2L1 Q07817 1/20 0.43
PLK4 O00444 1/20 0.41
AURKA O14965 1/20 0.41
DAPK3 O43293 1/20 0.41
CHEK2 O96017 1/20 0.41
CDK1 P06493 1/20 0.41
PIM1 P11309 1/20 0.41
PRKACA P17612 1/20 0.41
CDK2 P24941 1/20 0.41
MAPK9 P45984 1/20 0.41
CSNK1D P48730 1/20 0.41
GSK3A P49840 1/20 0.41
GSK3B P49841 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21092213 0.81 GPR35 (0.54) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL16769661 0.80 GPR35 (0.43) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL26967303 0.78 GPR35 (0.50) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL12668159 0.78 DAO (0.53) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL1659859 0.78 GPR35 (0.50) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL9405053 0.78 GPR35 (0.50) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL12606667 0.77 GPR35 (1.00) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL18270783 0.77 GPR35 (0.48) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL18264118 0.77 DAO (0.52) GPR35DAOALDH1A1KDM4EMEN1
SCHEMBL18264048 0.77 GPR35 (0.48) GPR35DAOALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074141-A1 POROUS MATERIAL AND APPLICATION THEREOF 华为技术有限公司 2024-04-11 WO claimed
CN-119565569-A Porous material and application thereof 华为技术有限公司 2025-03-07 CN disclosed
WO-2024074141-A1 POROUS MATERIAL AND APPLICATION THEREOF 华为技术有限公司 2024-04-11 WO disclosed
US-20220023829-A1 AMORPHOUS METAL ORGANIC FRAMEWORKS AND METHODS OF PREPARING THE SAME ABSORPTION SOLUTIONS LLC 2022-01-27 US disclosed
WO-2020117833-A2 AMORPHOUS METAL ORGANIC FRAMEWORKS AND METHODS OF PREPARING THE SAME FRAMERGY INC. (US) 2020-06-11 WO disclosed
EP-3514159-A1 ALUMINIUM METAL ORGANIC FRAMEWORK MATERIAL The Texas A&M University System (US) 2019-07-24 EP disclosed
EP-3143033-B1 CHROMIUM METAL ORGANIC FRAMEWORKS AND SYNTHESIS OF METAL ORGANIC FRAMEWORKS TEXAS A & M UNIV SYS (US) 2019-04-10 EP disclosed
US-9951095-B2 Chromium metal organic frameworks and synthesis of metal organic frameworks THE TEXAS A&M UNIVERSITY SYSTEM (US) 2018-04-24 US disclosed
US-9724668-B2 Iron metal organic framework materials THE TEXAS A&M UNIVERSITY SYSTEM (US) 2017-08-08 US disclosed
US-20170050995-A1 Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks THE TEXAS A&M UNIVERSITY SYSTEM 2017-02-23 US disclosed
US-20160346759-A1 Iron Metal Organic Framework Materials U.S. DEPARTMENT OF ENERGY 2016-12-01 US disclosed
EP-2876112-B1 Monocrystalline iron metal organic frameworks TEXAS A & M UNIV SYS (US) 2016-07-13 EP disclosed
WO-2015177511-A1 METHOD OF PREPARING A METAL ORGANIC FRAMEWORK THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-11-26 WO disclosed
WO-2015173553-A1 Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-11-19 WO disclosed
US-9102691-B2 Aluminum metal organic framework materials TEXAS A&M UNIVERSITY SYSTEM (US) 2015-08-11 US disclosed
US-20150152123-A1 Aluminum Metal Organic Framework Materials U.S. DEPARTMENT OF ENERGY 2015-06-04 US disclosed
WO-2015079229-A1 PROCESS FOR PREPARING METAL ORGANIC FRAMEWORK MATERIALS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-06-04 WO disclosed
WO-2015079230-A1 ALUMINIUM METAL ORGANIC FRAMEWORK MATERIALS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-06-04 WO disclosed
EP-2876112-A1 Monocrystalline iron metal organic frameworks THE TEXAS A & M UNIVERSITY SYSTEM (US) 2015-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170050995-A1 Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks OXGR1, TFRC, PICALM GPR35 1912/4885DAO 1245/4885ALDH1A1 2898/4885
US-20160346759-A1 Iron Metal Organic Framework Materials TFRC, FTH1, FECH GPR35 4539/4885DAO 2609/4885ALDH1A1 3550/4885
US-20150152123-A1 Aluminum Metal Organic Framework Materials AS3MT, ORAI2, ORAI3 GPR35 3951/4885DAO 2070/4885ALDH1A1 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.