Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28956061 | 0.81 | KDM4E (0.41) | KDM4EHPGDL3MBTL1MAPTPOLB | |
| SCHEMBL25232351 | 0.79 | ALDH1A1 (0.40) | KDM4EHSD17B10HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL30426841 | 0.79 | ALDH1A1 (0.47) | KDM4EHPGDL3MBTL1POLBALDH1A1 | |
| SCHEMBL3573409 | 0.75 | RAB9A (0.45) | KDM4EHSD17B10HPGDL3MBTL1MAPT | |
| SCHEMBL31434587 | 0.75 | MEN1 (0.40) | KDM4EL3MBTL1POLBALDH1A1 | |
| SCHEMBL3825257 | 0.73 | CYP4F2 (0.44) | KDM4EHSD17B10HPGDPOLBALDH1A1 | |
| SCHEMBL29211546 | 0.71 | RBP4 (0.46) | KDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL21577583 | 0.71 | KDM4E (0.39) | KDM4EL3MBTL1POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL5811947 | 0.69 | SMN1; SMN2 (0.70) | MAPTNPC1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL28354347 | 0.69 | KDM4E (0.56) | KDM4ESMN1; SMN2STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551841-A | Azetidin-3-ylcarbinol derivatives as modulators of the CCR6 receptor | 爱杜西亚药品有限公司 | 2022-12-30 | — | — | CN | disclosed |