Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426841 | 0.82 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL31434479 | 0.78 | BCHE (0.34) | KMT2ABCHEALDH1A1L3MBTL1GAA | |
| SCHEMBL25232351 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL28956062 | 0.75 | KDM4E (0.40) | ALDH1A1POLBKDM4EL3MBTL1 | |
| SCHEMBL28956061 | 0.75 | KDM4E (0.41) | MEN1KMT2AALDH1A1POLBKDM4E | |
| Hydrochloric Acid SCHEMBL29015997 | 0.71 | ALOX15 (0.41) | MEN1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL789538 | 0.71 | ALOX15 (0.41) | MEN1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL8354088 | 0.71 | SMYD2 (0.36) | ALDH1A1TSHRKDM4ETDP1LMNA | |
| SCHEMBL8350263 | 0.70 | SMYD2 (0.34) | ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL7336991 | 0.70 | SMYD2 (0.38) | ALDH1A1POLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051241-A1 | MACROCYCLIC COMPOUND AND ANTIBODY-DRUG CONJUGATE THEREOF | 劲方医药科技(上海)股份有限公司 | 2025-03-13 | — | — | WO | disclosed |