Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.85 |
| ▸ | CA9 | Q16790 | 16/20 | 0.85 |
| ▸ | CA1 | P00915 | 14/20 | 0.85 |
| ▸ | CA12 | O43570 | 13/20 | 0.85 |
| ▸ | CA7 | P43166 | 7/20 | 0.85 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.85 |
| ▸ | CA5A | P35218 | 5/20 | 0.85 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.85 |
| ▸ | CA6 | P23280 | 4/20 | 0.85 |
| ▸ | CA4 | P22748 | 4/20 | 0.85 |
| ▸ | TSHR | P16473 | 3/20 | 0.85 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL2798899 | 0.92 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL31544839 | 0.92 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL740 | 0.92 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL30659052 | 0.92 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL28284601 | 0.91 | CA2 (0.71) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL5894222 | 0.90 | CA2 (0.94) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL1155220 | 0.90 | CA2 (0.94) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL3273308 | 0.90 | CA2 (0.94) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL22501553 | 0.90 | CA2 (0.94) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL8030126 | 0.90 | CA2 (0.94) | CA2CA9CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114166826-A | Method for rapidly determining Chinese medicinal materials through sulfur fumigation | 商丘市食品药品检验检测中心 | 2022-03-11 | — | — | CN | claimed |
| CN-114166826-A | Method for rapidly determining Chinese medicinal materials through sulfur fumigation | 商丘市食品药品检验检测中心 | 2022-03-11 | — | — | CN | disclosed |