Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819289 | 0.85 | CYP2C9 (0.43) | TAS2R14CYP2C9MEN1KMT2AGAA | |
| SCHEMBL28143221 | 0.75 | ALDH1A1 (0.54) | CYP2C9RAB9AMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL2927951 | 0.74 | CYP2C9 (0.50) | HDAC6CYP2C9MEN1KMT2AGAA | |
| SCHEMBL6630838 | 0.72 | TAS2R14 (0.46) | TAS2R14DHODHHDAC6CTSSKDM4E | |
| SCHEMBL18965951 | 0.71 | TAS2R14 (0.45) | TAS2R14DHODHHDAC6CTSSGAA | |
| SCHEMBL28326071 | 0.71 | MEN1 (0.43) | CYP2C9MEN1KMT2AGAALMNA | |
| SCHEMBL7088402 | 0.70 | CYP2C9 (0.49) | TAS2R14CYP2C9MEN1KMT2AGAA | |
| SCHEMBL4454721 | 0.69 | KMT2A (0.44) | CYP2C9MEN1KMT2ALMNAMAPT | |
| Benzylic Acid SCHEMBL4823051 | 0.68 | CYP2C9 (0.65) | HDAC6CYP2C9MEN1KMT2AGAA | |
| SCHEMBL697951 | 0.68 | TAS2R14 (0.67) | TAS2R14DHODHHDAC6CTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311843-A | Azabenzimidazoles derivative as PI3K beta inhibitor | 詹森药业有限公司 | 2019-02-05 | — | — | CN | disclosed |