SCHEMBL697951

SCHEMBL697951

Cc1c(C(=O)O)cccc1C(F)(F)F

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 3/20 0.67
DHODH Q02127 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
CTSS P25774 1/20 0.51
FABP4 P15090 1/20 0.49
TSHR P16473 1/20 0.47
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SORT1 Q99523 1/20 0.44
ALOX15 P16050 1/20 0.43
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15352107 0.98 TAS2R14 (0.65) TAS2R14DHODHHDAC6CTSSFABP4
SCHEMBL28052031 0.86 TAS2R14 (0.55) TAS2R14DHODHHDAC6CTSSLMNA
SCHEMBL29656425 0.85 TAS2R14 (0.54) TAS2R14DHODHHDAC6CTSSLMNA
SCHEMBL12327907 0.85 TAS2R14 (0.54) TAS2R14DHODHHDAC6CTSSLMNA
SCHEMBL1966015 0.84 TAS2R14 (0.58) TAS2R14DHODHHDAC6FABP4LMNA
SCHEMBL29629424 0.83 TAS2R14 (0.53) TAS2R14DHODHHDAC6CTSSTSHR
SCHEMBL2576656 0.83 TAS2R14 (0.53) TAS2R14DHODHHDAC6CTSSTSHR
SCHEMBL5370256 0.83 TAS2R14 (0.53) TAS2R14DHODHHDAC6CTSSLMNA
SCHEMBL10397067 0.82 TSHR (0.49) TAS2R14DHODHHDAC6TSHRLMNA
SCHEMBL10053348 0.82 TAS2R14 (0.51) TAS2R14DHODHHDAC6ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
CN-110088108-A SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS 利奥制药有限公司 2019-08-02 CN claimed
US-20060128984-A1 Method of preparing an ester of an aromatic carboxylic acid bearing at least one perfluoroalkyl group CHIMIE, RHODIA (FR) 2006-06-15 US claimed
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 US disclosed
EP-4655296-A1 CBL-B INHIBITORS Aurigene Oncology Limited (IN) 2025-12-03 EP disclosed
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 US disclosed
US-20250230147-A1 LACTAMS AS CBL-B INHIBITORS GENENTECH, INC. (US) 2025-07-17 US disclosed
US-12325697-B2 CBL-B modulators and uses thereof NIMBUS CLIO, INC. (US) 2025-06-10 US disclosed
EP-4562016-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
EP-4267574-B1 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS AJAX THERAPEUTICS INC (US) 2025-04-23 EP disclosed
US-12247027-B2 P2X7 modulators JANSSEN PHARMACEUTICA NV (BE) 2025-03-11 US disclosed
US-20040176361-A1 Fused heterocyclic compound and medicinal use thereof MITSUBISHI PHARMA CORPORATION (JP) 2004-09-09 US disclosed
US-20040176433-A1 treatment of tumor necrosis factor mediated disorders; asthma; inflammatory bowel disease; arthritis PHARMACIA CORPORATION 2004-09-09 US disclosed
EP-1396488-A1 FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2004-03-10 EP disclosed
JP-2004002337-A METHOD FOR PRODUCING METHYLTRIFLUOROMETHYLBENZOIC ACID CENTRAL GLASS CO LTD 2004-01-08 JP disclosed
US-6617324-B1 Phenyl, cyclohexyl and pyridinyl or pyrimidinyl-substituted G. D. SEARLE & COMPANY 2003-09-09 US disclosed
US-6525059-B1 Mitogen-activated protein kinases (MAP); G. D. SEARLE & COMPANY 2003-02-25 US disclosed
US-6514977-B1 For treating p38 kinase mediated disorders G.D. SEARLE & COMPANY 2003-02-04 US disclosed
US-6423713-B1 Substituted pyrazoles as p38 kinase inhibitors G. D. SEARLE & COMPANY 2002-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 TAS2R14 4738/4885DHODH 1894/4885HDAC6 444/4885
US-12247027-B2 P2X7 modulators P2RX2, P2RX7, P2RY2 TAS2R14 2225/4885DHODH 3071/4885HDAC6 2726/4885
US-20250230147-A1 LACTAMS AS CBL-B INHIBITORS CBLB, CBL, CBLC TAS2R14 4317/4885DHODH 2481/4885HDAC6 3024/4885
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC TAS2R14 4229/4885DHODH 2951/4885HDAC6 2635/4885
US-20040176433-A1 treatment of tumor necrosis factor mediated disorders; asthma; inflammatory bowel disease; arthritis MAPK1, IL1R1, TNF TAS2R14 2867/4885DHODH 2034/4885HDAC6 2347/4885
US-20040176361-A1 Fused heterocyclic compound and medicinal use thereof PARP11, PARP1, CD38 TAS2R14 3992/4885DHODH 60/4885HDAC6 55/4885
US-12325697-B2 CBL-B modulators and uses thereof CBLB, CBL, CBLC TAS2R14 4229/4885DHODH 2951/4885HDAC6 2635/4885
US-20060128984-A1 Method of preparing an ester of an aromatic carboxylic acid bearing at least one perfluoroalkyl group ALK, PAH, PFAS TAS2R14 1989/4885DHODH 1032/4885HDAC6 4079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.