Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889430 | 0.90 | GPR119 (0.44) | ALOX5APGPR119FEN1 | |
| SCHEMBL2889678 | 0.89 | ALOX5AP (0.44) | ALOX5APGPR119FEN1PRMT5 | |
| SCHEMBL13290330 | 0.89 | ALOX5AP (0.44) | ALOX5APGPR119FEN1PRMT5 | |
| SCHEMBL27936838 | 0.87 | ABHD6 (0.50) | ALOX5APGPR119CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL938055 | 0.87 | ABHD6 (0.50) | ALOX5APGPR119CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL938053 | 0.87 | ABHD6 (0.50) | ALOX5APGPR119CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4324225 | 0.86 | LTA4H (0.48) | ALOX5APGPR119KDM1AABHD6DAGLA | |
| SCHEMBL4324219 | 0.86 | LTA4H (0.48) | ALOX5APGPR119KDM1AABHD6DAGLA | |
| SCHEMBL2889418 | 0.84 | GPR119 (0.46) | ALOX5APGPR119FEN1KDM1A | |
| SCHEMBL4318335 | 0.83 | GPR119 (0.49) | ALOX5APGPR119CHRNB4CHRNA3FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728032-B2 | Phenoxymethylalkyne inhibitors of LTA4H for treating inflammation | DECODE GENETICS EHF (IS) | 2010-06-01 | — | — | US | disclosed |
| US-20080090839-A1 | PHENOXYMETHYLALKYNE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF. (IS) | 2008-04-17 | — | — | US | disclosed |
| WO-2008019284-A1 | PHENOXYMETHYLALKYNE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090839-A1 | PHENOXYMETHYLALKYNE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | LTA4H, LTB4R, LTB4R2 | ALOX5AP 17/4885GPR119 1290/4885CHRNB1 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.