Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.47 |
| ▸ | DRD3 | P35462 | 11/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30125283 | 1.00 | DRD2 (0.47) | DRD2DRD3ABCC9ABCC8KCNJ11 | |
| SCHEMBL29655979 | 0.85 | DRD2 (0.48) | DRD2DRD3ABCC9ABCC8KCNJ11 | |
| SCHEMBL28590630 | 0.85 | DRD2 (0.48) | DRD2DRD3ABCC9ABCC8KCNJ11 | |
| SCHEMBL31083652 | 0.82 | DRD2 (0.47) | DRD2DRD3ABCC9ABCC8KCNJ11 | |
| SCHEMBL29729003 | 0.81 | DRD2 (0.34) | DRD2DRD3KDM1A | |
| SCHEMBL25359232 | 0.81 | DRD2 (0.54) | DRD2DRD3ABCC9ABCC8KCNJ11 | |
| SCHEMBL28958183 | 0.77 | CYP11B2 (0.39) | TSHRKDM1AMAOAMAOBENPP2 | |
| SCHEMBL22926165 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL4875328 | 0.73 | DRD2 (0.67) | DRD2DRD3ABCC9ABCC8KCNJ11 | |
| SCHEMBL8688588 | 0.72 | DRD2 (0.51) | DRD2DRD3ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115584516-A | Method for electrochemically inducing defluorination carboxylation reaction of difluorocyclopropane | 南京林业大学 | 2023-01-10 | — | — | CN | claimed |
| CN-115584516-A | Method for electrochemically inducing defluorination carboxylation reaction of difluorocyclopropane | 南京林业大学 | 2023-01-10 | — | — | CN | disclosed |