Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883367 | 0.79 | MGLL (0.40) | MGLLFAAHHSP90AA1ALDH1A1MAPT | |
| SCHEMBL29999825 | 0.79 | MGLL (0.40) | MGLLFAAHHSP90AA1ALDH1A1MAPT | |
| SCHEMBL397529 | 0.78 | TSHR (0.52) | MGLLHSP90AA1TLR9ALDH1A1MAPT | |
| SCHEMBL29364961 | 0.78 | TSHR (0.52) | MGLLHSP90AA1TLR9ALDH1A1MAPT | |
| SCHEMBL28883442 | 0.77 | MGLL (0.44) | MGLLFAAHDPP4NR1H2NR1H3 | |
| SCHEMBL28883404 | 0.77 | MGLL (0.44) | MGLLFAAHDPP4NR1H2NR1H3 | |
| SCHEMBL2032898 | 0.77 | MGLL (0.63) | MGLLFAAHHSP90AA1DPP4NR1H2 | |
| SCHEMBL21826723 | 0.76 | TLR9 (0.52) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL31179986 | 0.76 | TLR9 (0.52) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL28883370 | 0.75 | MGLL (0.51) | MGLLHSP90AA1TLR9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |