Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883367 | 1.00 | MGLL (0.40) | MGLLFAAHHSP90AA1ERN1RXFP1 | |
| SCHEMBL28958654 | 0.79 | MGLL (0.51) | MGLLFAAHHSP90AA1LMNACYP2A6 | |
| SCHEMBL28883404 | 0.75 | MGLL (0.44) | MGLLFAAH | |
| SCHEMBL28883442 | 0.70 | MGLL (0.44) | MGLLFAAHCYP2A6KDM4EALDH1A1 | |
| SCHEMBL2032898 | 0.69 | MGLL (0.63) | MGLLFAAHHSP90AA1LMNA | |
| SCHEMBL28883390 | 0.65 | MGLL (0.49) | MGLLFAAHHSP90AA1ALDH1A1MAPT | |
| SCHEMBL7845940 | 0.64 | ERN1 (0.50) | HSP90AA1ERN1RXFP1CYP2A6SIRT2 | |
| SCHEMBL3675670 | 0.64 | MGLL (0.56) | MGLLFAAHHSP90AA1ALDH1A1 | |
| SCHEMBL56836 | 0.63 | CYP2A6 (0.57) | ERN1RXFP1CYP2A6NCEH1KDM4E | |
| SCHEMBL22863431 | 0.63 | MGLL (0.46) | MGLLFAAHHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |