Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392929 | 0.94 | ATM (0.45) | ATMITGA4ITGB7ACEAKT1 | |
| SCHEMBL9321962 | 0.94 | ATM (0.45) | ATMITGA4ITGB7ACEAKT1 | |
| SCHEMBL11651226 | 0.94 | ATM (0.45) | ATMITGA4ITGB7ACEAKT1 | |
| SCHEMBL6548736 | 0.89 | ITGA4 (0.44) | ATMITGA4ITGB7ACEAKT1 | |
| SCHEMBL18076338 | 0.87 | TPSAB1 (0.47) | ATMITGA4ITGB7ACEL3MBTL1 | |
| SCHEMBL9551347 | 0.86 | AKT1 (0.39) | ATMITGA4ITGB7ACEAKT1 | |
| SCHEMBL11047397 | 0.85 | SLC7A5 (0.48) | ATMITGA4ITGB7ACECTSS | |
| SCHEMBL8472422 | 0.84 | ALDH1A1 (0.48) | ATMITGA4ITGB7ACEAKT1 | |
| SCHEMBL8472423 | 0.84 | ALDH1A1 (0.48) | ATMITGA4ITGB7ACEAKT1 | |
| SCHEMBL18359864 | 0.84 | ALDH1A1 (0.48) | ATMITGA4ITGB7ACEAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160380-B | Compound capable of controlling CO release rate and preparation method thereof | 西安交通大学医学院第一附属医院 | 2024-06-21 | — | — | CN | disclosed |
| CN-115160380-A | Compound capable of controlling CO release rate and preparation method thereof | 西安交通大学医学院第一附属医院 | 2022-10-11 | — | — | CN | disclosed |