Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321962 | 0.92 | ATM (0.45) | ITGA4ITGB7SLC7A5ATMACE | |
| SCHEMBL11651226 | 0.92 | ATM (0.45) | ITGA4ITGB7SLC7A5ATMACE | |
| SCHEMBL8392929 | 0.92 | ATM (0.45) | ITGA4ITGB7SLC7A5ATMACE | |
| SCHEMBL7273450 | 0.90 | SLC7A5 (0.43) | ITGA4ITGB7SLC7A5CTSSCTSK | |
| SCHEMBL6549571 | 0.90 | CTSS (0.44) | ITGA4ITGB7SLC7A5ACECTSS | |
| SCHEMBL28958862 | 0.89 | ATM (0.43) | ITGA4ITGB7SLC7A5ATMACE | |
| SCHEMBL6550882 | 0.88 | CTSK (0.43) | ITGA4ITGB7SLC7A5CTSSCTSK | |
| SCHEMBL7273304 | 0.86 | ALOX5 (0.36) | ITGA4ITGB7SLC7A5PTGS1CTSS | |
| SCHEMBL11047397 | 0.86 | SLC7A5 (0.48) | ITGA4ITGB7SLC7A5ATMACE | |
| SCHEMBL9259844 | 0.85 | MAOB (0.39) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480946-A2 | A HYDROXAMIC ACID THROMBOSPONDIN PEPTIDE ANALOG THAT INHIBITS AGGRECANASE ACTIVITY | MP Biomedicals, L.L.C. (US) | 2004-12-01 | — | — | EP | disclosed |
| US-20030114529-A1 | HO-NH-(C=O)-CH2-CH(-CH2-CH(CH3)2)-(C=O)-V-,V=valine or another amino acid connected with an amino acid sequence of 10 or more amino acids; useful for treating diseases caused by cartilage degradation | MP BIOMEDICALS, LLC | 2003-06-19 | — | — | US | disclosed |
| WO-2003005956-A2 | A HYDROXAMIC ACID THROMBOSPONDIN PEPTIDE ANALOG THAT INHIBITS AGGRECANASE ACTIVITY | ENZYME SYSTEMS PRODUCTS, INC. /(ICN - BIOMEDICALS) (US) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114529-A1 | HO-NH-(C=O)-CH2-CH(-CH2-CH(CH3)2)-(C=O)-V-,V=valine or another amino acid connected with an amino acid sequence of 10 or more amino acids; useful for treating diseases caused by cartilage degradation | HGFAC, ASPH, SYVN1 | ITGA4 3570/4885ITGB7 3828/4885SLC7A5 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.