SCHEMBL28959532

SCHEMBL28959532

CC(C)(C)OC(=O)C(C)(C)NC(=O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.43
CA14 Q9ULX7 1/20 0.39
CA2 P00918 1/20 0.36
CTSK P43235 1/20 0.33
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8155897 0.76 DGAT1 (0.48) DGAT1MEN1KMT2A
SCHEMBL1714208 0.74 DGAT1 (0.50) DGAT1CA14CTSKALDH1A1SMN1; SMN2
SCHEMBL4463196 0.73 KDM4C (0.42) CA14CA2ALDH1A1POLBSMN1; SMN2
Hydrochloric Acid SCHEMBL28000852 0.72 DGAT1 (0.48) DGAT1CA14CTSKSMN1; SMN2
Hydrochloric Acid SCHEMBL4469009 0.71 KDM4C (0.41) CA14CA2ALDH1A1POLBSMN1; SMN2
SCHEMBL4469005 0.71 CA2 (0.40) CA14CA2ALDH1A1POLBSMN1; SMN2
SCHEMBL20882727 0.71 DGAT1 (0.43) DGAT1CA14CA2ALDH1A1MEN1
SCHEMBL10013884 0.71 DGAT1 (0.36) DGAT1
SCHEMBL18334532 0.71 CA14 (0.46) DGAT1CA14CA2CTSKALDH1A1
SCHEMBL16976213 0.70 DGAT1 (0.52) DGAT1CA2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
EP-4056580-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-09-14 EP disclosed
CN-114630835-A Process for the preparation of peptide compounds comprising sterically bulky amino acids 中外制药株式会社 2022-06-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid DNPEP, VIP, NPEPPS DGAT1 3349/4885CA14 1972/4885CA2 3659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.