SCHEMBL2896199

SCHEMBL2896199

CC1(OC(=O)c2ccc(-c3ccccc3)cc2)CC2C=CC1C2

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
GAA P10253 1/20 0.37
MAPT P10636 3/20 0.37
FSHR P23945 1/20 0.37
KDM4E B2RXH2 2/20 0.37
EGFR P00533 1/20 0.36
TSHR P16473 2/20 0.36
KMT2A Q03164 1/20 0.36
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
CCR2 P41597 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2893711 0.92 GAA (0.43) GAAMAPTTSHRKMT2ACCR2
SCHEMBL2901038 0.89 MAPT (0.41) MAPTCCR2
SCHEMBL2892928 0.82 SCN1A (0.50) SCN1ASCN2ASCN3ASMN1; SMN2GAA
SCHEMBL2899258 0.82 MAPT (0.40) SMN1; SMN2MAPTKDM4ETSHRRAB9A
SCHEMBL200205 0.79 KDM4E (0.43) PDCD1CD274SCN1ASCN2ASCN3A
SCHEMBL7863152 0.76 CYP2D6 (0.36)
SCHEMBL2892925 0.75 ALDH1A1 (0.38) MAPTKDM4EKMT2ACCR2ALDH1A1
SCHEMBL2899391 0.75 KMT2A (0.42) GAAKDM4EKMT2ARAB9ANPC1
SCHEMBL1720274 0.72 NPC1 (0.37) RAB9ANPC1
SCHEMBL4103952 0.72 KMT2A (0.43) SMN1; SMN2GAAMAPTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
US-7101498-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US disclosed
US-6846890-B2 Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040242824-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING OPENING POLYMERIZATION JSR CORPORATION (JP) 2004-12-02 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1459107-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-09-22 EP disclosed
EP-1435350-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING-OPENING POLYMERIZATION JSR Corporation (JP) 2004-07-07 EP disclosed
WO-2003056365-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2003-07-10 WO disclosed