SCHEMBL2899258

SCHEMBL2899258

CC1(OC(=O)c2ccc3ccccc3c2)CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
HRH3 Q9Y5N1 2/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 1/20 0.38
PTPN1 P18031 1/20 0.38
DRD3 P35462 1/20 0.37
SLC6A3 Q01959 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
LGALS9 O00182 1/20 0.35
LGALS8 O00214 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2893711 0.84 GAA (0.43) MAPTTSHRLMNA
SCHEMBL2896199 0.82 PDCD1 (0.41) MAPTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL2892925 0.81 ALDH1A1 (0.38) MAPTHPGDKDM4ESLC6A3ALDH1A1
SCHEMBL200989 0.80 HRH3 (0.44) MAPTHRH3CES2CES1NPC1
SCHEMBL4934163 0.78 HRH3 (0.47) MAPTHRH3CES2CES1NPC1
SCHEMBL2899391 0.78 KMT2A (0.42) HRH3NPC1RAB9AHPGDKDM4E
SCHEMBL22822742 0.72 HSP90AA1 (0.46) MAPTHRH3CES2CES1NPC1
SCHEMBL4100310 0.72 L3MBTL1 (0.43) MAPTRAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL7863152 0.71 CYP2D6 (0.36)
SCHEMBL1720397 0.71 SLC6A4 (0.39) SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
US-7101498-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US disclosed
US-6846890-B2 Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040242824-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING OPENING POLYMERIZATION JSR CORPORATION (JP) 2004-12-02 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1459107-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-09-22 EP disclosed
EP-1435350-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING-OPENING POLYMERIZATION JSR Corporation (JP) 2004-07-07 EP disclosed
WO-2003056365-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2003-07-10 WO disclosed