Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928981 | 0.94 | MEN1 (0.44) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL22361237 | 0.83 | MEN1 (0.64) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL28962253 | 0.78 | HDAC4 (0.39) | MEN1MAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL28928982 | 0.77 | MAOA (0.45) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL77179 | 0.77 | CYP1B1 (0.61) | MEN1MAPTKMT2ACYP1B1ALDH1A1 | |
| SCHEMBL29583035 | 0.77 | CYP1B1 (0.61) | MEN1MAPTKMT2ACYP1B1ALDH1A1 | |
| SCHEMBL2842601 | 0.75 | KMT2A (0.61) | MEN1MAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL30165987 | 0.75 | KMT2A (0.61) | MEN1MAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL29095873 | 0.73 | ALDH1A1 (0.40) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL28928969 | 0.73 | PARP1 (0.38) | MEN1MAPTKMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583876-B | Phenyl naphthacene ketone compound and preparation method and application thereof | 深圳技术大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-115583876-A | Phenyl-naphthalenepophenone compounds, preparation method and application thereof | 深圳技术大学 | 2023-01-10 | — | — | CN | disclosed |