Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 14/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962249 | 0.83 | MEN1 (0.44) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL28928982 | 0.80 | MAOA (0.45) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL29583035 | 0.79 | CYP1B1 (0.61) | MEN1MAPTKMT2ACYP1B1ALDH1A1 | |
| SCHEMBL77179 | 0.79 | CYP1B1 (0.61) | MEN1MAPTKMT2ACYP1B1ALDH1A1 | |
| SCHEMBL16225115 | 0.78 | MEN1 (1.00) | MEN1MAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL30184802 | 0.78 | MEN1 (1.00) | MEN1MAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL28928981 | 0.77 | MEN1 (0.44) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL29095873 | 0.76 | ALDH1A1 (0.40) | MEN1MAPTKMT2AMAPK1CYP1B1 | |
| SCHEMBL10350796 | 0.74 | PABPC1 (0.58) | MEN1MAPTKMT2ACYP1B1ALDH1A1 | |
| SCHEMBL28938488 | 0.74 | CYP1B1 (0.44) | MEN1MAPTKMT2ACYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699224-A1 | SCORCH RETARDANT HALOGENATED FLAME RETARDANT COMPOUNDS AND ARTICLES MADE THEREFROM | PolyOne Corporation (US) | 2020-08-26 | — | — | EP | disclosed |