Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983333 | 0.81 | SMPD1 (0.54) | LMNASMN1; SMN2KDM4ESMPD1HDAC1 | |
| SCHEMBL874091 | 0.75 | HTT (0.55) | LMNASMN1; SMN2KDM4ESMPD1HDAC1 | |
| SCHEMBL159448 | 0.75 | HTT (0.55) | LMNASMN1; SMN2KDM4ESMPD1HDAC1 | |
| SCHEMBL1656948 | 0.74 | SMPD1 (0.53) | LMNASMN1; SMN2KDM4ESMPD1HDAC1 | |
| SCHEMBL7048751 | 0.74 | SMPD1 (0.53) | LMNASMN1; SMN2KDM4ESMPD1HDAC1 | |
| SCHEMBL30211021 | 0.73 | CTSV (0.60) | SMN1; SMN2KDM4ECYP1A2SMPD1HDAC1 | |
| SCHEMBL8039259 | 0.71 | LMNA (0.51) | LMNASMN1; SMN2SMPD1HDAC1HDAC8 | |
| SCHEMBL23459152 | 0.71 | KDM4E (0.52) | SMN1; SMN2KDM4ESMPD1HDAC1HDAC8 | |
| SCHEMBL2089698 | 0.71 | KDM4E (0.52) | SMN1; SMN2KDM4ESMPD1HDAC1HDAC8 | |
| SCHEMBL873729 | 0.70 | MEN1 (0.57) | LMNAKDM4ESMPD1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677701-A | Benzo heterocyclic compound and preparation method and application thereof | 昆药集团股份有限公司 | 2023-02-03 | — | — | CN | disclosed |