Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939516 | 0.84 | FLT4 (0.62) | FLT4KDRTSHRLMNAMKNK1 | |
| SCHEMBL29728010 | 0.83 | ADORA2A (0.60) | KDRLMNAEP300ALDH1A1EGFR | |
| SCHEMBL1565498 | 0.83 | ADORA2A (0.60) | KDRLMNAEP300ALDH1A1EGFR | |
| SCHEMBL28950122 | 0.82 | KDR (0.46) | FLT4KDRALDH1A1P2RX7EGFR | |
| SCHEMBL27967584 | 0.73 | TMIGD3 (0.65) | TSHRRAB9ANPC1HTTKMT2A | |
| SCHEMBL8646398 | 0.73 | FLT4 (0.50) | FLT4KDRTSHRMKNK1RAB9A | |
| SCHEMBL28313408 | 0.73 | FDPS (0.49) | TSHRLMNARAB9ANPC1KDM4E | |
| SCHEMBL28950092 | 0.72 | ADORA2A (0.66) | TSHRADORA2AADORA1AHCY | |
| SCHEMBL14611764 | 0.72 | CDK1 (0.48) | TSHRLMNARAB9ANPC1RXFP1 | |
| SCHEMBL6694591 | 0.71 | EGFR (0.60) | KDRALDH1A1EGFRADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677807-A | 6-position alpha-hydroxyalkylated purine compounds and methods for modification thereof | 鲁东大学 | 2023-02-03 | — | — | CN | disclosed |