Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | AHCY | P23526 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28964589 | 0.82 | FLT4 (0.44) | KDRFLT4EGFRP2RX7AHCY | |
| SCHEMBL27713663 | 0.80 | EGFR (0.64) | KDREGFRAHCYADORA2AADORA1 | |
| SCHEMBL28020916 | 0.80 | P2RX7 (0.64) | KDRFLT4EGFRP2RX7AHCY | |
| SCHEMBL28950092 | 0.78 | ADORA2A (0.66) | AHCYADORA2AADORA1CYP1A2CYP2D6 | |
| SCHEMBL28950118 | 0.74 | AHCY (0.48) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL28950089 | 0.74 | NPC1 (0.50) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL28950094 | 0.72 | ADORA2A (0.65) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28950076 | 0.72 | CSNK2A1 (0.49) | AHCYADORA2AADORA1ALDH1A1CYP1A2 | |
| SCHEMBL455646 | 0.70 | P2RX7 (0.49) | KDRFLT4EGFRP2RX7ADORA2A | |
| SCHEMBL28126755 | 0.69 | FDPS (0.55) | KDRFLT4EGFRP2RX7ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677807-A | 6-position alpha-hydroxyalkylated purine compounds and methods for modification thereof | 鲁东大学 | 2023-02-03 | — | — | CN | disclosed |