Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TAS2R46 | P59540 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953088 | 0.79 | TAS2R46 (0.46) | PKMTAS2R46TDP1MEN1RECQL | |
| SCHEMBL29114432 | 0.69 | TXNRD1 (0.40) | PKMTXNRD1TAS2R46TDP1MEN1 | |
| SCHEMBL30444013 | 0.68 | PKM (0.56) | PKMTAS2R46TDP1MEN1RECQL | |
| SCHEMBL29842294 | 0.68 | TXNRD1 (0.52) | PKMTXNRD1TAS2R46TDP1MEN1 | |
| Tatridin B SCHEMBL29602987 | 0.63 | TXNRD1 (0.59) | PKMTXNRD1TAS2R46TDP1MEN1 | |
| SCHEMBL31487118 | 0.62 | PKM (0.74) | PKMTAS2R46TDP1MEN1RECQL | |
| SCHEMBL13344975 | 0.61 | TXNRD1 (0.40) | TXNRD1TDP1TERTCYP3A4 | |
| SCHEMBL12703841 | 0.61 | TXNRD1 (0.40) | TXNRD1TDP1TERTCYP3A4 | |
| Salonitenolide SCHEMBL29391892 | 0.60 | PTPN1 (0.51) | PKMTXNRD1TAS2R46TDP1MEN1 | |
| SCHEMBL17815616 | 0.59 | PKM (0.61) | PKMMEN1KMT2ACYP2D6NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057679-B | 4 novel sesquiterpene lactone compounds separated from burdock leaves and preparation method and application thereof | 河南中医药大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-114057679-A | 4 new sesquiterpene lactone compounds separated from burdock leaves and preparation method and application thereof | 河南中医药大学 | 2022-02-18 | — | — | CN | disclosed |