SCHEMBL28965232

SCHEMBL28965232

CCC1(C(=O)OC)CC=CC=C1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
KDM4E B2RXH2 3/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TACR1 P25103 1/20 0.37
TACR3 P29371 1/20 0.37
OPRM1 P35372 5/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CHRM1 P11229 2/20 0.34
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28172298 0.80 MEN1 (0.39) MAPTTACR1TACR3OPRM1MEN1
SCHEMBL4245698 0.78 ATM (0.34) MAPTATML3MBTL1OPRM1MEN1
SCHEMBL9858334 0.75 TSHR (0.36) MAPTOPRM1MEN1KMT2ACHRM1
SCHEMBL28737049 0.74 SMN1; SMN2 (0.47) KDM4EATMOPRM1SMN1; SMN2OPRD1
SCHEMBL27636757 0.73 OPRM1 (0.43) OPRM1SMN1; SMN2OPRD1OPRK1
SCHEMBL31119236 0.72 DGAT1 (0.38) MAPTL3MBTL1TSHRSMN1; SMN2
SCHEMBL7684826 0.71 USP2 (0.34) MEN1KMT2AALDH1A1CYP3A4CYP2C19
SCHEMBL29908101 0.71
SCHEMBL5050534 0.71 ATM (0.42) MAPTKDM4EATML3MBTL1OPRM1
SCHEMBL27501957 0.70 P2RX7 (0.44) MAPTKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710210-A Iron catalyzed amination of C-H bonds 港大科桥有限公司 2023-02-24 CN disclosed