Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28172298 | 0.90 | MEN1 (0.39) | TSHRCHRM1CYP3A4KMT2AMEN1 | |
| SCHEMBL9052363 | 0.87 | KMO (0.36) | TSHRCYP3A4KMT2AMEN1LMNA | |
| SCHEMBL9861595 | 0.77 | SMN1; SMN2 (0.35) | CYP3A4KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL505430 | 0.77 | AKR1C1 (0.35) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28737049 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2OPRM1 | |
| SCHEMBL28176754 | 0.76 | PDCD1 (0.41) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL27599522 | 0.75 | AKR1C1 (0.34) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28965232 | 0.75 | MAPT (0.40) | TSHRCHRM1CYP3A4KMT2AMEN1 | |
| SCHEMBL30223732 | 0.73 | KMO (0.34) | TSHRCYP3A4KMT2AMEN1LMNA | |
| SCHEMBL7684826 | 0.71 | USP2 (0.34) | TSHRCYP3A4KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407808-A2 | Catalyst, process for preparation of same, and process for polymerization of olefins using same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-01-16 | — | — | EP | disclosed |