Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | ERN1 | O75460 | 5/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PMM2 | O15305 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406706 | 0.80 | MEN1 (0.55) | AKR1C3ERN1PDK2MEN1KMT2A | |
| SCHEMBL29495930 | 0.79 | AKR1C3 (0.51) | AKR1C3AKR1C2MEN1KMT2AALDH1A1 | |
| SCHEMBL1195462 | 0.79 | AKR1C3 (0.51) | AKR1C3AKR1C2MEN1KMT2AALDH1A1 | |
| SCHEMBL1169066 | 0.77 | AKR1C3 (0.72) | AKR1C3AKR1C2HPGDPTGS1PTGS2 | |
| SCHEMBL255000 | 0.76 | CES2 (0.61) | ERN1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL477610 | 0.76 | AKR1C3 (0.51) | AKR1C3AKR1C2ALDH1A1PTGS1PTGS2 | |
| SCHEMBL29482201 | 0.76 | CES2 (0.61) | ERN1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20560610 | 0.74 | AKR1C3 (0.50) | AKR1C3AKR1C2KMT2ASMN1; SMN2PTGS1 | |
| SCHEMBL2645114 | 0.73 | ERN1 (0.47) | AKR1C3ERN1PDK2MEN1KMT2A | |
| SCHEMBL31365131 | 0.73 | MEN1 (0.49) | ERN1MEN1KMT2APMM2MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115803316-A | Pyridone compound and preparation method and application thereof | 深圳晶泰科技有限公司 | 2023-03-14 | — | — | CN | disclosed |