SCHEMBL28967474

SCHEMBL28967474

CCOP(OCC)c1c2ccccc2nn1-c1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MPO P05164 3/20 0.46
HTT P42858 2/20 0.46
ADORA3 P0DMS8 6/20 0.44
ADORA1 P30542 5/20 0.44
ADORA2A P29274 2/20 0.44
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 2/20 0.39
PDE10A Q9Y233 1/20 0.38
MAOB P27338 1/20 0.38
PDE4D Q08499 1/20 0.38
CA9 Q16790 1/20 0.38
POLB P06746 1/20 0.38
GRIK2 Q13002 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28967467 0.88 MPO (0.51) MPOADORA3ADORA1ADORA2AALDH1A1
SCHEMBL28967455 0.87 MPO (0.41) MPOADORA3ADORA1ADORA2AKMT2A
SCHEMBL28967458 0.86 ESR2 (0.43) MPOHTTADORA3ADORA2ACYP3A4
SCHEMBL28967452 0.86 RAB9A (0.41) MPOHTTADORA3ADORA2AMEN1
SCHEMBL28967453 0.86 PTGS1 (0.43) MPOMEN1KMT2AALDH1A1
SCHEMBL28967480 0.85 MPO (0.44) MPOHTTMEN1KMT2AALDH1A1
SCHEMBL28967477 0.82 FGFR1 (0.46) ADORA3MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL28967479 0.81 TP53 (0.40) MEN1KMT2AALDH1A1PDE4D
SCHEMBL28967462 0.80 GAA (0.44) MPOHTTCYP1A2CYP2D6CYP2C9
SCHEMBL28967463 0.79 MPO (0.41) MPOHTTADORA3ADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613060-A Method for synthesizing C-3 phosphorylated 2H-indazole compound by direct electrochemical oxidation 浙江工业大学 2023-01-17 CN disclosed