SCHEMBL28967477

SCHEMBL28967477

CCOP(OCC)c1c2ccccc2nn1-c1ccc(C(=O)OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.46
POLB P06746 3/20 0.46
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
KDM4A O75164 1/20 0.42
TLR7 Q9NYK1 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
MAPK1 P28482 1/20 0.40
DRD2 P14416 2/20 0.39
TBXA2R P21731 2/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28967467 0.83 MPO (0.51) ALDH1A1L3MBTL1ADORA3MAPK1
SCHEMBL28967474 0.82 MPO (0.46) POLBALDH1A1ADORA3MEN1KMT2A
SCHEMBL28967455 0.82 MPO (0.41) ALDH1A1HPGDKDM4EGAAMAPT
SCHEMBL28967452 0.81 RAB9A (0.41) KDM4EGAAMAPTSMN1; SMN2NPC1
SCHEMBL28967458 0.81 ESR2 (0.43) ALDH1A1GAAMAPTTLR7SMN1; SMN2
SCHEMBL28967453 0.81 PTGS1 (0.43) ALDH1A1HPGDKDM4EMAPTRAB9A
SCHEMBL28967469 0.75 MPO (0.58) FGFR1ALDH1A1HPGDKDM4EGAA
SCHEMBL28967462 0.75 GAA (0.44) ALDH1A1KDM4EGAAL3MBTL1IDO1
SCHEMBL28967463 0.74 MPO (0.41) ALDH1A1ADORA3
SCHEMBL28967451 0.72 ADORA3 (0.38) ALDH1A1KDM4EMAPTL3MBTL1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613060-A Method for synthesizing C-3 phosphorylated 2H-indazole compound by direct electrochemical oxidation 浙江工业大学 2023-01-17 CN disclosed