SCHEMBL28967463

SCHEMBL28967463

CCOP(OCC)c1c2ccccc2nn1-c1cccc(C)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MPO P05164 3/20 0.41
ADORA3 P0DMS8 4/20 0.41
ADORA1 P30542 4/20 0.41
ADORA2A P29274 2/20 0.41
ALDH1A1 P00352 2/20 0.39
NPBWR1 P48145 1/20 0.38
MCHR1 Q99705 1/20 0.38
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ELANE P08246 1/20 0.37
RPA1 P27694 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28967467 0.87 MPO (0.51) MPOADORA3ADORA1ADORA2AALDH1A1
SCHEMBL28967469 0.86 MPO (0.58) MPOADORA1ALDH1A1LMNAHTT
SCHEMBL28967455 0.86 MPO (0.41) MPOADORA3ADORA1ADORA2AALDH1A1
SCHEMBL28967454 0.82 STAT1 (0.43) MPOLMNAPKMHTT
SCHEMBL28967462 0.81 GAA (0.44) MPOALDH1A1TSHRHTTRPA1
SCHEMBL28967458 0.80 ESR2 (0.43) MPOADORA3ADORA2AALDH1A1LMNA
SCHEMBL28967452 0.80 RAB9A (0.41) MPOADORA3ADORA2ALMNATSHR
SCHEMBL28967453 0.80 PTGS1 (0.43) MPOALDH1A1ELANE
SCHEMBL28967474 0.79 MPO (0.46) MPOADORA3ADORA1ADORA2AALDH1A1
SCHEMBL28967451 0.78 ADORA3 (0.38) MPOADORA3ADORA2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613060-A Method for synthesizing C-3 phosphorylated 2H-indazole compound by direct electrochemical oxidation 浙江工业大学 2023-01-17 CN disclosed