Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179407 | 1.00 | PRMT1 (0.42) | PRMT1ALDH1A1FGFR1DDB1CRBN | |
| SCHEMBL12651236 | 0.84 | HTR7 (0.43) | ALDH1A1ALOX5CYP2C9HTR7CYP3A4 | |
| SCHEMBL1787047 | 0.80 | ALDH1A1 (0.51) | ALDH1A1DDB1CRBNALOX5MEN1 | |
| SCHEMBL13060961 | 0.80 | TRIM24 (0.48) | ALDH1A1DDB1CRBNPOLB | |
| SCHEMBL23173798 | 0.78 | CRBN (0.66) | PRMT1ALDH1A1FGFR1DDB1CRBN | |
| SCHEMBL1965858 | 0.78 | DDB1 (0.61) | ALDH1A1DDB1CRBNALOX5HCRTR1 | |
| SCHEMBL7344849 | 0.78 | ALOX5 (0.59) | ALDH1A1ALOX5CYP2C9HTR7CYP3A4 | |
| SCHEMBL5056229 | 0.78 | ALOX5 (0.50) | ALDH1A1DDB1CRBNALOX5HCRTR1 | |
| SCHEMBL150081 | 0.77 | ALOX5 (0.60) | ALOX5DRD2DRD3MEN1POLB | |
| SCHEMBL18367729 | 0.77 | ALDH1A1 (0.46) | PRMT1ALDH1A1FGFR1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772175-A | Thieno-ring compounds, process for their preparation and their use | 中国科学院分子细胞科学卓越创新中心 | 2023-03-10 | — | — | CN | disclosed |