Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.54 |
| ▸ | HTR3B | O95264 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7840760 | 0.83 | ALOX5 (0.54) | ALOX5MAPTCYP2C9CYP2C19HTR1A | |
| SCHEMBL5056229 | 0.82 | ALOX5 (0.50) | ALOX5MAPTALDH1A1DRD2MEN1 | |
| SCHEMBL1965858 | 0.82 | DDB1 (0.61) | ALOX5MAPTCYP2C9CYP2C19HTR1A | |
| SCHEMBL150081 | 0.81 | ALOX5 (0.60) | ALOX5MAPTADRB1DRD2MEN1 | |
| SCHEMBL1787047 | 0.81 | ALDH1A1 (0.51) | ALOX5ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5182221 | 0.81 | FAAH (0.47) | ALOX5MAPTCYP2C9CYP2C19HTR1A | |
| SCHEMBL2723456 | 0.79 | HTR3E (0.47) | ALOX5HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27945523 | 0.79 | HTR1A (0.54) | ALOX5CYP2C9CYP2C19HTR1ACYP2D6 | |
| SCHEMBL26090921 | 0.79 | ALOX5 (0.49) | ALOX5MAPTCYP2C9CYP2C19HTR1A | |
| SCHEMBL30910130 | 0.79 | ALOX5 (0.49) | ALOX5MAPTCYP2C9CYP2C19HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115584070-A | Anti-aging polymer composition and application thereof | 江苏永顺新材料科技有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-115214041-B | Environment-friendly emission-free melting co-extrusion granulation production process and application thereof | 江苏永顺新材料科技有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-115584070-A | Anti-aging polymer composition and application thereof | 江苏永顺新材料科技有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-115214041-A | Environment-friendly emission-free melt co-extrusion granulation production process and application thereof | 江苏永顺新材料科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| US-6331636-B1 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, DIABETES, HYPERTENSION, IMPOTENCY, APPETITE CONTROL | THE UPJOHN COMPANY | 2001-12-18 | — | — | US | disclosed |
| EP-0623114-B1 | PHENYL IMIDAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS 5HT3 RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN SPA (IT) | 1999-05-06 | — | — | EP | disclosed |
| US-5545755-A | USEFUL TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS, HYPERTENSION, DIABETES, SEXUAL IMPOTENCY AND TO CONTROL APPETITE | THE UPJOHN COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| US-5424328-A | Treatment of central nervous system disorders | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-06-13 | — | — | US | disclosed |
| EP-0623114-A1 | PHENYL-IMIDAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS 5HT3 RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1994-11-09 | — | — | EP | disclosed |
| WO-1994011347-A1 | PHENYL-IMIDAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS 5HT3 RECEPTOR ANTAGONISTS | FARMITALIA CARLO ERBA SRL (IT) | 1994-05-26 | — | — | WO | disclosed |
| EP-0536279-A1 | SUBSTITUTED 1-(ALKOXYPHENYL)PIPERAZINES WITH CNS AND ANTIHYPERTENSIVE ACTIVITY | THE UPJOHN COMPANY (US) | 1993-04-14 | — | — | EP | disclosed |
| EP-0476016-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1992000282-A1 | SUBSTITUTED 1-(ALKOXYPHENYL)PIPERAZINES WITH CNS AND ANTIHYPERTENSIVE ACTIVITY | THE UPJOHN COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |
| WO-1990015047-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |
| US-4642351-A | TREATMENT OF OXAZOLIDINONE WITH ISOCYANATE OR ISOTHIOCYANATE | THE DOW CHEMICAL COMPANY (US) | 1987-02-10 | — | — | US | disclosed |
| US-4107304-A | Oxo-imidazolidine substituted cephalosporins and antibacterial compositions and methods of combatting bacteria employing them | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |
| US-4093722-A | ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4086340-A | ANTIBIOTIC; ANIMAL GROWTH PROMOTER | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-25 | — | — | US | disclosed |
| US-4031229-A | SUBSTITUTED IMIDAZOLIDINONE-PENICILLANIC ACIDS, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |
| US-4011238-A | CNS DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1977-03-08 | — | — | US | disclosed |