Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 6/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.49 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.49 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.48 |
| ▸ | INSR | P06213 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | TTK | P33981 | 2/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28885516 | 0.80 | NCF1 (0.54) | CSF1RRETNEK2 | |
| SCHEMBL30880547 | 0.78 | PDGFRA (0.49) | CSF1REGFRRET | |
| SCHEMBL30880656 | 0.77 | PDGFRA (0.48) | CSF1REGFRRET | |
| SCHEMBL4703621 | 0.76 | NEK2 (0.61) | NEK2 | |
| SCHEMBL30880630 | 0.76 | MAPK10 (0.51) | MAPK10EGFR | |
| SCHEMBL11029725 | 0.75 | CCNA2 (0.58) | CDK2CCNA2PLK1CCNA1PLK3 | |
| SCHEMBL28431630 | 0.75 | SRC (0.59) | CSF1REGFRRET | |
| SCHEMBL26086217 | 0.74 | RAD52 (0.49) | CDK2CCNA1IGF1REGFRTTK | |
| SCHEMBL28968037 | 0.73 | EGFR (0.50) | CSF1REGFRRET | |
| SCHEMBL30340614 | 0.72 | ADRA2A (0.63) | MAPK10CDK2IGF1REGFRDYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466211-B | N-phenylquinoline-4-amine compound and application thereof | 中国人民解放军空军军医大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-115466211-A | N-phenylquinoline-4-amine compound and application thereof | 中国人民解放军空军军医大学 | 2022-12-13 | — | — | CN | disclosed |