Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF114 | Q9Y508 | 1/20 | 0.64 |
| ▸ | YAP1 | P46937 | 2/20 | 0.59 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 3/20 | 0.47 |
| ▸ | BECN1 | Q14457 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969681 | 0.89 | RNF114 (0.70) | RNF114YAP1TEAD4L3MBTL1CACNA1H | |
| SCHEMBL25122626 | 0.81 | RNF114 (0.83) | RNF114YAP1TEAD4L3MBTL1CACNA1H | |
| SCHEMBL23518782 | 0.78 | RNF114 (0.78) | RNF114YAP1TEAD4L3MBTL1CACNA1H | |
| SCHEMBL27465865 | 0.77 | RNF114 (0.88) | RNF114YAP1TEAD4L3MBTL1NPSR1 | |
| SCHEMBL29129845 | 0.77 | RNF114 (0.69) | RNF114YAP1TEAD4L3MBTL1CACNA1H | |
| SCHEMBL23518678 | 0.76 | RNF114 (0.91) | RNF114YAP1TEAD4L3MBTL1CACNA1H | |
| SCHEMBL25810589 | 0.76 | HDAC8 (0.49) | L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30688878 | 0.75 | RNF114 (0.88) | RNF114YAP1TEAD4CACNA1HBCL2 | |
| SCHEMBL16938347 | 0.68 | MEN1 (0.68) | RNF114YAP1TEAD4L3MBTL1NPSR1 | |
| SCHEMBL22013863 | 0.68 | MAPT (0.50) | L3MBTL1KDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819423-A | ProTAC compound of Reidesciclovir or intermediate thereof, preparation method thereof and application of anti-EV 71 | 武汉大学 | 2023-03-21 | — | — | CN | disclosed |